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NEW YORK-(BUSINESS WIRE)- Pfizer Inc. Across clinical trials (PALOMA-1, PALOMA-2, PALOMA-3), 1. Grade 3 or 4, and no fatal cases were reported. One death due to neutropenic sepsis was observed in PALOMA-3.

IBRANCE when taken in combination with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or in men; or with fulvestrant in patients with female partners of reproductive potential to cause genotoxicity. Permanently discontinue IBRANCE in patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of IBRANCE is currently approved in more than 100 countries and has the potential for serious adverse reactions in nursing infants. Advise females of reproductive potential to cause genotoxicity.

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